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Clarksdale is a small city located in the northwest region of Mississippi, United States. Known as the birthplace of the blues, Clarksdale attracts music lovers from all over the world to its many live music venues and annual festivals. The city is also home to several historical landmarks, including the Delta Blues Museum and the famous Crossroad intersecting Highways 61 and 49. Clarksdale offers visitors a glimpse into the heart of the Mississippi Delta, with its rich culture, delicious southern cuisine, and friendly locals.